Scientific Research | Promensil

Scientific Research

The Promensil Range has been developed to help women through specific stages of the menopause.

  • Backed by over 15 years of Scientific Research
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A large number of studies have been conducted on over 1’000 women by specialists at universities and teaching hospitals under close ethical supervision, in accordance with the Good Clinical Research Practice guidelines.]

Studies related to women’s health and menopause

A number of studies have been carried out to assess effects of red clover supplementation in women going through menopause, namely effects on its symptoms. [5, 6, 7, 8].

Bone health

The bone preserving properties of Red clover have been examined in several randomized, placebo-controlled trials, demonstrating a positive effect of Red clover on bone mineral density as well as an increase in bone formation markers. [4].

Heart health

The vascular effects of Red clover as potential contributors to the heart protective properties were studied in two 12 week, double-blind, randomised trials on postmenopausal women. [1, 2].

A 12 week, double-blind, randomised, dose-escalating study was conducted to investigate the effects of two dose levels of the Red clover formulation (40 mg and 80 mg) versus placebo on arterial compliance. [3].


1. Effects of isoflavone phytoestrogens on lipid profile in postmenopausal Peruvian women. Abstract presented at the International Menopause Society Conference, Berlin 2002. Jeri A. Paper presented at: 9th International Menopause Society World Congress on the Menopause; October 20, 1999; Yokahama, Japan. 2. Influence of Red clover-derived isoflavones on serum lipid profile in postmenopausal women. Terzic MM, Dotlic J, Maricic S, Mihailovic T, Tosic-Race B. J Obstet Gynaecol Res. 2009 Dec;35(6):1091-5. 3. Isoflavones from Red clover improve systemic arterial compliance but not plasma lipids in menopausal women. Nestel PJ, Pomeroy S, Kay S, Komesaroff P, Behrsing J, Cameron JD, West L Journal of Clinical Endocrinology and Metabolism 1999 4. The effects of phytoestrogen isoflavones on bone density in women: A double-blind, randomized, placebo-controlled trial. American Journal of Clinical Nutrition. 2004. Atkinson C, Compston JE, Day NE, Dowsett Mand Bingham SA. 5. Isoflavones from Red clover (Promensil) significantly reduce menopausal hot flush symptoms compared with placebo. Maturitas 2002. Van de Weijer et al. 6. The use of an Isoflavone supplement to relieve hot flushes. The Female Patient 2002. Jeri. 7. Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from Red clover extracts. Maturitas. 2010 Mar;65(3):258-61. Epub 2009 Nov 30. Lipovac M, Chedraui P, Gruenhut C, Gocan A, Stammler M, Imhof M 8. Effects of red dover isoflavones (Promensil) versus placebo on uterine endometrium, vaginal maturation index and the uterine artery in health postmenopausal women. Journal of the British Menopause Society 2003. Woods R, Colville N, Blazquez J, Cooper A, Whitehead MI